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CSL [ASX: CSL]

Navigating Global R&D and Pharmacokinetics in Oncology

Rose Fida, Executive Director and Regional Lead of R&D for Japan & China at CSL, is an innovative leader with extensive experience in drug development, R&D governance, and strategic project management. With a steadfast commitment to advancing treatments for unmet medical needs, Rose drives impactful research programs across the Asia-Pacific region, driving innnovation to improve patient outcomes. In an exclusive interview with Life Sciences Review APAC, Rose shares her perspective regarding the industry, sharing valuable insights into current developments, emerging challenges, and the future of therapeutic innovation. 1. Can you share your professional journey and the experiences that led you to your current role at CSL? Growing up, I had a natural aptitude for mathematics and a passion for science and medicine. Despite winning a university-level maths competition at 15, a teacher advised me not to pursue science or maths, saying these weren’t “careers for girls.” That moment became defining—it fuelled my determination to prove that gender should never limit ambition. Fortunately, my parents encouraged me to pursue a biomedical career. After my Honours degree, I earned a PhD in Physiology, focusing on serotonin in colonic motility. I then joined the Victorian College of Pharmacy as a Senior Scientist, working in pharmacokinetics—a field I initially knew little about. With supportive colleagues, I learned that success depends not on entering industry with a complete skill set, but on a willingness to learn. After 18 months, I became Pharmacokinetics Team Leader, sparking my enduring interest in drug development. A personal turning point came when my father was diagnosed with cancer, which shifted my career to oncology drug development. At Mayne Pharma, I became Global Project Leader within 2.5 years, despite having no initial project management experience. Later, at Cytopia, I gained broad exposure to clinical, regulatory, and research domain

Digital Magazine

Navigating Global R&D and Pharmacokinetics in Oncology

Drug Discovery and Development

Thousand Oaks Biologics

Scaling Biologics through Integrated Manufacturing Systems

Shun Luo, Founder, Chairman and President

What challenges limit the ability to scale biologics manufacturing for widespread patient access? The science of biologics has never moved faster. Therapeutic modalities are multiplying, targeting is growing more precise and molecular architectures are becoming more complex. The discovery engine is running at full speed, but the path to manufacturing remains a bottleneck. Manufacturing complex biologics with the consistency and cost required to reach patients broadly remains a challenge in pharmaceutical development. Most of the industry treats that problem as someone else’s. Thousand Oaks Biologics was founded on the premise that manufacturing is where biologic innovation either scales or stalls. “The competitive edge isn’t just at the innovation stage,” says Shun Luo, founder, chairman and president. “It will also be at the commercialization stage. And commercialization is manufacturing.” That conviction shapes how Thousand Oaks Biologics is built. It is an integrated contract research, development and manufacturing organization (CRDMO). Its capabilities span the full arc, from early antibody discovery and cell line engineering to chemistry, manufacturing and controls (CMC) development, good manufacturing practice (GMP) production and commercial supply. Every capability is owned. Every stage connects. The system advantage is its molecule-first architecture, where every process is designed around the specific biologic it serves..

Next-Generation Sequencing

ROKIT Genomics

Accelerating Breakthroughs in Single-Cell Science

TaeWoo Kwon, CEO

The field of single-cell transcriptomics is growing rapidly, driven by the need to understand cellular heterogeneity better. As it expands, researchers are increasingly challenged by the complexity of the technologies and data involved. One of the most critical and often overlooked challenges is tissue dissociation. Unlike bulk RNA-seq, which provides an averaged gene expression profile across thousands of cells, scRNA-seq requires a precise, customized approach at every step. Different tissues, species and models, such as organoids, make applying a one-size-fits-all isolation protocol impossible. In addition, many researchers lack a background in computational biology or coding, which limits their ability to extract insight from complex data. ROKIT Genomics addresses these challenges by stepping into the researcher’s shoes. Drawing on published methods and pilot studies, the team identifies the most effective strategies to ensure optimal tissue dissociation, even in the most intricate biological systems. Its flexible multiplexing strategies, (including antibody-, probe-, and non-labeling-based methods) allow multiple samples to be processed simultaneously with a single reagent set, significantly improving cost-efficiency and throughput. Supporting a wide range of platforms, including 10x Genomics, BD Rhapsody and MobiDrop, it adapts to the unique needs of every project. As a designated reference lab for BD Biosciences, the team is also among the first to deploy and validate emerging applications, ensuring clients benefit from the latest advancements in the field. Its support often extends to project design, troubleshooting and manuscript preparation. The pre-analysis consultation ensures that clients receive the most relevant results..

Drug Discovery and Development

Dunwill Medical

Biomarkers That Deliver Real Results

Sofia Wen, Founder and CEO

Every year, the medical field witnesses promising discoveries—new molecules, novel biomarkers, and breakthrough technologies that promise earlier diagnoses and more effective treatments. Despite the hope they carry, many of these discoveries never make it to the patients who need them most. They remain confined to research papers, circulating in academic circles, but falling short of delivering practical value in the clinic. Physicians continue to face unanswered questions, laboratories accumulate unused findings, and patients wait for tools that could transform their care. Dunwill Medical was founded to break this cycle. The company’s mission is to ensure that the enormous potential of biomarker research is translated into real-world diagnostic products that physicians and patients can trust. By positioning itself at the intersection of clinical practice, cutting-edge science, and industrialization expertise, Dunwill ensures that ideas born in the laboratory are transformed into solutions that directly improve outcomes at the bedside. “Our best R&D capability is not to create a fancy idea,” says Sofia Wen, founder and CEO. “It is to take a doctor’s idea and bring it to life as a dependable IVD product.” Innovation Rooted in Clinical Practice The cornerstone of Dunwill’s approach is what the company describes as its “Stronger together” model. Its innovation process begins in the hospital, at the point of patient care. The first step in every project is not a new piece of technology or an abstract research idea, but the real challenges that physicians and surgeons encounter daily. If a surgeon struggles with unclear diagnostic results or if a physician faces limitations in current testing methods, that pain point becomes the starting point for Dunwill’s work. By partnering with clinicians, listening to their needs, and involving them from the earliest stages, the company ensures that the developed solutions are immediately relevant, practical, and actionable. This model is compelling in China, where translational medical research has advanced internationally. Chinese hospitals and research institutes are increasingly recognized as leaders in basic and applied medical science. Dunwill leverages this ecosystem by collaborating with some of the nation’s most respected hospitals and clinical experts. Through these collaborations, the company can identify unmet clinical needs, connect them with emerging biomarker discoveries, and then apply its proven industrialization capabilities to transform those discoveries into finished diagnostic products..

Therapeutics

Beyond Distribution-Distributors Value in Healthcare Ecosystem

Ziteng Zhang, Senior Distribution Manager, West China (Rotation), CSL

Therapeutics

Evolving Digital Biomarkers in Clinical Trial Space

Kazuto Yamada, Senior Director, Head of Clinical Development Planning and Supervising Five R&D Functions, Otsuka Pharmaceutical

Life Science Consulting

The Strategic Role of Compliance in Organizations: Leveraging the Importance of Compliance in Healthcare Companies

uliana Steinhart, Legal, Compliance & Data Privacy Director, Merz Aesthetics

Drug Discovery and Development

Emphasizing the Importance of Assuring Product Quality

Raymond R. Tjandrawinata, Director of Business Development and Scientific Affairs, Dexa Medica

Clinical Trial Management

Building Better Health Through Innovation and Leadership

Lotus Mallbris, Senior Vice President, Business Unit Leader - Immunology Japan, Eli Lilly and Company

IN MY OPINION

Therapeutics

Modular approach for Large Scale Cell Culture CDMO facilities

Jacob Gronnegaard, Director Automation, FUJIFILM Diosynth Biotechnologies

LAST WORD

Biomanufacturing

Quality Assurance: Navigating the Escalating Compliance Complexities

Imelda Rillon, Corporate Head of Quality & HSSE, Zuellig Pharma

IN FOCUS

Quality and Compliance: APAC's Biopharmaceutical CDMO Landscape

Biopharmaceutical CDMOs provide specialized expertise, scalable manufacturing, and access to advanced technologies.

Learn more

Immunotherapy in APAC: Bridging Research and Clinical Practice for Cancer Care

Immunotherapy harnesses the immune system to effectively fight cancer, evolving through research, clinical trials, and personalized treatment strategies.

Learn more

EDITORIAL

Engineering Scale in Biopharmaceuticals

Biopharmaceutical innovation is accelerating, yet manufacturing continues to define how effectively discovery translates into patient access. In this edition of Life Sciences Review APAC, the focus shifts to integrated development and manufacturing systems that are reshaping scalability, cost and speed. As molecular complexity increases, aligning research with production is no longer optional but essential. Process integration, quality assurance and system-level design are emerging as the mechanisms that enable continuity from early discovery through commercial supply.

At the forefront of this issue, Thousand Oaks Biologics, recognized as the Biopharmaceutical CDMO of the Year in Asia 2026, exemplifies this shift through an integrated manufacturing model built around the molecule itself. Its CRDMO framework connects cell culture media development, cell line engineering, CMC processes and GMP production into a single system, enabling faster timelines and improved scalability. By applying continuous perfusion technology at scale, it increases yield, reduces cost and enables complex biologics to move more efficiently toward commercialization.

This emphasis on integration extends across the broader biopharmaceutical value chain, where operational discipline and system integrity are becoming central to sustained outcomes. Raymond R. Tjandrawinata, Director of Business Development and Scientific Affairs at Dexa Medica, underscores the role of rigorous quality assurance, traceability and regulatory oversight in ensuring product safety. Complementing this perspective, Lotus Mallbris, Senior Vice President and Business Unit Leader - Immunology Japan at Eli Lilly and Company, highlights how localized insight, collaboration and purposedriven innovation are critical in accelerating patient access and aligning therapies with real-world needs.

As these perspectives converge, biopharmaceutical progress is increasingly defined by execution across integrated systems rather than isolated innovation. Organizations that align discovery, manufacturing and quality within structured frameworks are better positioned to sustain performance as complexity grows. Consistency now emerges from coordination, scientific rigor and operational discipline.

We invite readers to engage with these insights and assess how such approaches can be applied within their own development and manufacturing strategies.

Life Sciences Review APAC
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