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Life Science Review Weekly Brief

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ViroMissile: “One-Shot” Cure for Deadly Cancers

ViroMissile

“One-Shot” Cure for Deadly Cancers

Though medical science has come a long way over the years, cancer still remains a battle no one chooses but a war that many fight. The battlefield is grueling—multiple rounds of chemotherapy that drain the body, radiation that scorches healthy cells along with cancerous ones, and surgeries that leave both physical and emotional scars. Every treatment is a test of endurance, stretching over weeks, months, or even years. The process is exhausting, the side effects relentless, and the outcome uncertain. But what if treatment could be simpler and less grueling? What if a single breakthrough could turn the tide? ViroMissile’s groundbreaking innovation is rewriting the future of cancer treatment—paving the way for a potential one-shot solution. Built on the Intravenously Deliverable Oncolytic Virus (IDOV™) platform, the solution uses an oncolytic virus—a genetically engineered vaccinia virus—designed to selectively target and destroy cancer cells while simultaneously activating the body's immune response. The platform’s intravenous delivery ensures the virus reaches tumors throughout the body, overcoming the limitations of traditional oncolytic virus therapies. This approach represents a specialized form of immunotherapy with the potential to revolutionize cancer treatment. The genius behind this innovation is Dr. Nanhai George Chen, CEO of ViroMissile, who brings over 30 years of experience and award-winning early work in virotherapy to the forefront of cancer treatment. “Instead of designing hundreds of different therapies for hundreds of different cancer types, our solution is triggering the immune system and targeting fundamental characteristics of cancer—such as rapidly dividing cells—which makes the approach broadly applicable,” says Dr. Chen. Rather than developing highly customized treatments for each patient, the company is working toward a universal solution—one that could be effective across multiple types of cancer. That scalability has the potential to transform cancer treatment worldwide. Since launching its operations in 2018, ViroMissile has made remarkable progress. The company has developed a groundbreaking third generation of oncolytic viruses. Preclinical studies in mouse models have shown that a single injection can cure multiple cancers, and early clinical trials in China provide strong evidence that the virus successfully reaches tumors in human patients. Beyond the science, ViroMissile is built on a foundation of financial and operational efficiency. Initially a one-person startup, the company has grown steadily, attracting investment and expanding its expert team— comprising biotech veterans, clinical trial specialists, and strategic advisors—to support its groundbreaking work. This lean yet highly focused approach has enabled ViroMissile to achieve significant milestones without excessive overhead, positioning it well to address one of oncology’s toughest challenges. In doing so, the company not only aims to revolutionize cancer therapy but also to make advanced treatments accessible to a broader patient population. ViroMissile is the first company to demonstrate effective intravenous delivery of an oncolytic virus in both preclinical models and human patients—a significant milestone given that previous attempts have struggled to reach and infiltrate tumors after intravenous administration.

Digital Magazine

ViroMissile: “One-Shot” Cure for Deadly Cancers

Life Science Consulting

Murdock Martell

Empowering Startups in Life Sciences and MedTech

Claire Martell, CEO

Bringing groundbreaking products to market that improve patient well-being is always top of mind for medtech and life science startups. This requires an all-hands-on-deck approach where every last piece of available resource is dedicated to the business' core operations. At the same time, monitoring backend processes like finance management and human resources (HR) is essential to ensuring business continuity. While the task may seem daunting, Murdock Martell—a boutique consulting firm—makes it a cakewalk. The company specializes in finance, accounting and HR services, guiding startups and emerging companies from seed funding to exit. It also serves various technology sectors, including AI, robotics and semiconductors, offering customized solutions. Founders are often stretched thin during a startup's early stages. Murdock Martell helps them offload noncore functions and offers essential operational support by simplifying their financial processes. This includes putting together financial statements, providing assistance in cash management and giving insights on the cash burn rate to help companies understand how long their funds will last. These offerings improve the client’s efficiency, leading to financial stability. “We help the founders put together a very simplistic set of financials, handle ongoing reporting and assist them with their business needs,” says Claire Martell, CEO. Once a startup begins to grow, hiring becomes a priority. Establishing a strong HR infrastructure is necessary to recruit and retain talented professionals for long-term success and ensure compliance with legal requirements. The company’s dedicated HR resources are perfectly equipped to address these requirements. Once these companies mature and achieve regulatory approvals from the FDA, they transition from development to commercialization. As companies scale up operations and begin full production, they need efficient inventory tracking, management and supply chain operations to ensure consistent cash flow and meet the lead times to support revenue growth. Rather than moving forward with commercialization, some companies even opt for a sale after the FDA approval. Murdock Martell supports these clients with due diligence, helping them meet the expectations of investors, regulators and buyers..

BioTech

Faust Bio-Agricultural Services, Inc

Organic Agricultural Technology Derived from the Past

Robert H. Faust, Founder and President

Who has fully realized that history is not contained in thick books but lives in our very blood?” This excerpt from Carl Jung’s work feels more relevant than ever as the world contends with the impact of synthetic chemicals in agriculture. As a result, age-old organic farming practices are being revisited, and answers are often found in humanity’s ancient past. Seeking to bridge this ancient wisdom with modern science, Robert H. Faust founded Faust Bio-Agricultural Services, Inc (BioAg), aiming to demystify concepts like biodynamics and bring regenerative practices back to the forefront. BioAg transmuted the rediscovered knowledge to provide the agricultural sector with an alternative viable technology called biostimulants. It leads the organic biostimulant manufacturing sector, allowing cultivators to grow plants efficiently and reach their genetic potential. “Unlike fertilizers and other conventional chemicals, our biostimulants target the nucleus of the cell to increase growth and disease resistance,” says Faust, founder and president. BioAg frees farmers from using chemicals through a complete biostimulant package. It allows them to achieve better yields and meet organic crop regulatory standards regarding pesticide residue and heavy metals while reducing the use of synthetic or salt-based fertilizers/pesticides. The BioAg package includes fulvic and humic acids, amino acids, plant-available silicon, micronutrients, and microorganism-based solutions. BioAg’s Ful-Power humic acids act as nutrient-chelating agents, improving yield and quality by retaining key plant-supportive compounds such as aromatics, phenolic and carboxylic groups. Cal-Mino amino acids from enzymatically digested non-GMO soybeans offer an organic nitrogen source with carbon backbones that support nutrient formation, suitable for both conventional and organic farming. The company even offers plant-available silicon in dry and liquid forms, suitable for soil and foliar applications. Its product blends, like Bio-SuperSil, combine silicon with humic and fulvic acids to create effects not typically seen in other silicon-based solutions. Additionally, BioAg formulates specialized blends to combat micronutrient deficiencies, improving nutrient availability by complexing and chelating them during production..

CDMO

Abzena

Advancing Drug Development with a Hands-On Approach

Matt Stober, CEO

Abzena combines deep scientific expertise with a flexible, high-touch approach to help customers bring groundbreaking therapies to market. As a CRO and a CDMO, it integrates design, development and manufacturing under a single organization, supporting the advancement of complex biologics and bioconjugates. This end-to-end approach enables seamless progression from early discovery through phases one, two and three, strengthening regulatory readiness and accelerating the path to commercial manufacturing. Abzena’s specialized services include Antibody-drug conjugates (ADC) and Antibody-oligo conjugates (AOC), bi-specific and multi-specific antibodies, T-cell engagers and radiopharmaceuticals (RDC). Its proprietary linker technology, ThioBridge™ and advanced protein engineering capabilities ensure stability and scalability. The company’s cell line development platform, AbZelectPRO™, also delivers high-impact yields exceeding eight grams per liter before process intensification, ensuring efficiency and scalability as programs progress onwards into downstream development and manufacturing. “One thing that differentiates us as a drug development partner is that we get more involved with companies that may have a single target or a few programs in their pipeline,” says Matt Stober, CEO. “We understand how important these programs are to these companies, and we stay highly engaged with their leadership teams to ensure development moves along at the necessary pace for them to keep moving forward.” Abzena’s customer base is comprised of small and mid-sized biotech companies and large multi-national pharmaceutical firms. Leveraging the deep scientific expertise of its 450+ professionals, including 75 PhDs their global scientific teams work closely with customers to align projects with timelines and product performance goals to ensure a successful outcome. Guiding customers through the Investigational New Drug (IND) submission process is an essential regulatory step at which Abzena excels. Its expertise in IND-enabling work allows customers to enter clinical trials efficiently, helping them reach important milestones in their drug development journey. Delays and risks are minimized by staying ahead of evolving guidelines and incorporating regulatory feedback to ensure that supporting data, development processes, and documentation align with the latest standards. .

Biomanufacturing

Facilitating a Lessons Learned Session with your CMO

Yvonne Ware, Director, CMC, BioNTech SE

Therapeutics

Modular approach for Large Scale Cell Culture CDMO facilities

Jacob Gronnegaard, Director Automation, FUJIFILM Diosynth Biotechnologies

Cell and Gene Therapy

A Call To Action For Rare Diseases

Jeff Sherman, Chief Medical Officer, Horizon

Life Science Testing

Multidisciplinary Approach To Improving Breast Cancer Screening

Julie Singewald, Interim System Shared Clinical Services Operations Leader, Essentia Health

Therapeutics

Scaling The Future Of Sustainable Food Through Fermentation

Frances Gilman, Senior Manager of R&D, Next Generation Ingredients, Kraft Heinz

IN MY OPINION

Therapeutics

Gene Therapy-Therapeutic Viral Vectors; Manufacturing, Challenges, and Innovation

Rachel Legmann, PhD, Senior Director of Technology, Gene Therapy, Repligen Corp

LAST WORD

Therapeutics

Soli Organic's Recipe For Affordable, Indoor Organic Produce: The Right Blend Of Tech + Nature

Gianna De Caro, Chief Product Officer, Soli Organic

IN FOCUS

Breaking Barriers in Cancer Care: The Evolution of Innovative Platforms

Innovative cancer-targeting platforms have emerged as groundbreaking solutions in the battle against one of the most formidable diseases of our era.

Learn more

How CMOs Are Redefining Life Sciences Manufacturing

The life sciences industry, a sector dedicated to discovering, developing, and manufacturing products aimed at improving human health, operates within a framework of rigorous regulations and intricate processes.

Learn more

EDITORIAL

Cracking Cancer’s Code with Innovation

Once centered on traditional processes and timelines, the life sciences industry is now in the middle of a remarkable evolution—propelled by scientific breakthroughs and next-generation therapies. As the transformation unfolds, contract manufacturing organizations (CMO) have become pivotal in bridging innovation and commercialization through agile, cost-effective production. Their expertise in managing complex supply chains and compliance is especially vital in oncology, where speed and precision are important. By strengthening the link between innovation and patient access, CMOs are accelerating the delivery of advanced cancer treatments to global markets.

Cancer-fighting treatments continue to progress through the convergence of AI, precision oncology, immunotherapy and digital health. AI enhances early detection and treatment decisions through biomedical data analysis. Precision oncology targets previously untreatable mutations with next-generation therapies, while immunotherapy improves immune responses and digital tools support real-time patient monitoring.

Life sciences consulting firms apply scientific and regulatory expertise to assist pharmaceutical, biotech and agricultural companies in product development, compliance and market access. With a pulse on evolving research, these providers align innovation with strategy, ensuring successful product lifecycles across global markets.

In a similar vein, the agricultural life sciences domain is also advancing. Organic bio-stimulants, made from natural sources like seaweed and plant extracts, enhance plant growth, nutrient absorption and stress tolerance.

In this edition of Life Sciences Review, we spotlight the top players driving change, such as the top contract manufacturer, organic bio-stimulants manufacturing company, life science consulting provider and pioneering cancer destroying platform.

On the cover, we feature ViroMissile—the Top Cancer Destroying Platform of 2025. ViroMissile embodies a bold vision of a one-shot cure, blending science and hope through a breakthrough oncolytic virus platform that can transform how the world fights cancer.

This edition also features expert viewpoints that highlight the evolving dynamics of therapeutic manufacturing. Yvonne Ware, Associate Director at BioNTech, shares the value of strengthening CDMO partnerships and cross functional alignment. Rachel Legmann, PhD, Senior Director of Technology, Gene Therapy, at Repligen Corp explores the potential of next-gen platforms in overcoming viral vector production challenges. Their insights reflect a shared commitment to smarter, more resilient bioproduction.

As the life sciences industry evolves, cancer-defeating platforms, CMOs, and strategic consultants are shaping the future of global health. We hope this edition sparks fresh perspectives—share your thoughts and join the conversation.

Life Sciences Review APAC
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